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The epicenter of the coronavirus outbreak in the U.S. has spent weeks under strict restrictions. But the mayor says up to 400,000 people will likely return to their jobs soon — with some conditions.

Michigan has seen a surge in COVID-19 cases, and skepticism is growing over health orders and vaccines. Gov. Gretchen Whitmer is in persuasion mode to try to get vaccine skeptics on board.

The express passenger train partially derailed inside a mountain tunnel on Friday after reportedly hitting a truck that had slid from a hillside onto the track.

The possible plan could affect President Biden, among other Catholic political figures. The Vatican is calling for U.S. bishops to reach a consensus and says any such move could sow division.

Jeff Bezos gave $100 million each in "courage and civility awards" to CNN's Van Jones and chef José Andrés.

Blinken served as deputy secretary of state and deputy national security adviser under President Barack Obama. The announcement came along with a number of other national security picks.

Biden has named Ron Klain as his White House chief of staff. Klain has been a fixture in the White House and Democratic campaigns for decades.

The two departments have a key role in supporting American households. HUD has responsibility for affordable housing, while USDA oversees food assistance programs.

President Trump lost, but House Republicans had a better-than-anticipated 2020 election. They picked up at least eight seats and narrowed the House Democrats' majority.

The nation's biggest name-brand pharmacy chains face a high-profile civil trial beginning Monday in Ohio over their role in the nation's deadly opioid epidemic.